Untrastructural Morphology of Bovine Herpesvirus Infected Cells

Infectious bovine rhinotracheitis (IBR) virus has been shown to cause considerable economic losses in the South Dakota cattle industry. On the average, one in ten cattle abortions are caused by this virus. This amounts to approximately $250,000 lost each year by South Dakota cattlemen. There is no way of determining the economic loss due to the respiratory infections also caused by this virus. As is the case with most virus diseases, control requires extensive knowledge of its biological, physical and chemical properties. The present study was undertaken to determine the effect of IBR virus on the ultrastructure of a bovine cell culture. The work was designed to confirm the previously reported similarities of IBR virus with other herpesviruses and to resolve some of the discrepancies in the literature regarding cellular changes in response to herpesvirus infections