The research of the phytochemical composition of the fruits of Rosa (Rosa L.) genus plants.

R. Juodytė master‘s thesis. Supervisor Prof. Dr. Habil. Valdimaras Janulis; Lithuanian University of Health Sciences, Medical Academy, Faculty of Pharmacy, Department of Pharmacognosy, Kaunas. The title: The research of the phytochemical composition of the fruits of Rosa (Rosa L.) genus plants. The aim of the research: to determine the variation of the qualitative and quantitative composition of phenolic compounds of fruits samples of wild rose varieties grown in Lithuanian climatic conditions, and to evaluate the antioxidant activity of their extracts in vitro. The objectives of the research: to determine the conditions for extraction of phenolic compounds in fruit samples of wild rose varieties grown in Lithuania; to investigate the variation of hydroxycinnamic acid derivatives, flavonoids, total variation of phenolic compounds in fruit samples of wild rose varieties by spectrophotometric method; to evaluate the antioxidant activity of fruit samples of wild rose varieties grown in Lithuania in vitro by spectrophotometric method; to determine the qualitative and quantitative composition of phenolic compounds in fruit samples of wild rose varieties by high-performance liquid chromatography; The object and methods of the research: fruit samples of wild rose varieties grown in Lithuanian climatic conditions. The total content of phenolic compounds, hydroxycinnamic acid derivatives, flavonoids and antioxidant activity in vitro were determined using spectrophotometric methods. Quantitative and qualitative composition of phenolic compounds was determined by high-performance liquid chromatography. The results and conclusions of the research: The highest amount of total phenolic compounds were determined in the fruit samples of the Rosa pimpinellifolia L. “Single Cherry” (50.13±4.17 mg GRE/g, p<0.05) and were determined on 7 October (51.49±0.52 mg GRE/g, p<0.05), 23 September (51.4±1.72 mg GRE/g, p<0.05) and 9 September (45.84±1.22 mg GRE/g, p