Mechanic Thrombectomy in Acute Ischemic Stroke

Aim: To assess efficacy of mechanical thrombectomy in acute ischemic stroke Objectives: 1. To assess early results of mechanical thrombectomy in acute ischemic stroke. 2. To assess safety of mechanical thrombectomy treatment in acute ischemic stroke. 3. To assess efficacy on using mechanical thrombectomy in combination with standard care of acute ischemic stroke. Methods: A systematic review of available publications on MEDLINE database was conducted. The following search criteria were used: Clinical Review articles published within 10 years, written in English and with full text access with keywords „Thrombectomy stroke“. Only publications with primary analysis of clinical reviews that had perspective randomized trials exploring mechanical thrombectomy in treating acute ischemic stroke in comparison to standard care was chosen. Results: Search was conducted using PUBMED system with keywords „Thrombectomy stroke“. 4559 publications were found. After filtration, 264 publications remained with 4295 articles discarded. After reviewing titles and summaries, 254 more publications were put aside. 20 remaining articles were fully analysed and only 10 final publications chosen for systematic literature review. In total, 1904 patients were assessed. Conclusions: 1. There was statistical significance in early neurological improvement for patients treated with mechanical thrombectomy in comparison to intravenous thrombolysis. 2. There was no significant change in frequency of complications or death between mechanical thrombectomy and intravenous thrombolysis. 3. Mechanical thrombectomy had significantly higher efficacy at 90 day neurological disability assessment when compared to intravenous thrombolysis