Add to ORKGAbstract A new disposable, multiphase, microbioreactor (MBR; with a working volume of 550 μl) equipped with online sensors is presented for biotechnological screening research purposes owing to its high‐throughput potential. Its design and fabrication, online sensor integration, and operation are described. During aerobic cultivation, sufficient oxygen supply is the most important factor that influences growth and product formation. The MBR is a microbubble column bioreactor (μBC), and the oxygen supply was realized by active pneumatic bubble aeration, ensuring sufficient volumetric liquid‐phase mass transfer (kLa) and proper homogenization of the cultivation broth. The μBC was equipped with miniaturized sensors for the pH, dissolved oxyge...
Biotechnological processes are a key technology in the synthesis of high-grade chemicals and pharmac...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2005.Includes...
Accurate real-time process control is necessary to increase process efficiency, and optical sensors ...
Microbioreactors (MBRs) with a volume below 1 mL are promising alternatives to established cultivati...
In recent years, microbioreactor (MBR) systems have evolved towards versatile bioprocess engineering...
This thesis presents the design, fabrication, and characterization of a batch microbioreactor with i...
Abstract Bioprocessing is of crucial importance in pharmaceutical, biofuel, food and other industri...
Abstract- Over the years, microbioreactors have been equipped with a variety of tools for online mon...
Aerobic batch cultivations of Candida utilis were carried out in two micro bioreactors with a workin...
Shaken bioreactors are widespread in the field of biotechnology. Especially, microtiter plates are i...
The rising costs of bioprocess research and development emphasize the need for high-throughput, low-...
In the manufacture of bio-therapeutics the importance of a well-known process is key for a high prod...
Abstract: Two prototype 24-unit microbioreactors are presented and reviewed for their relative merit...
Two of the most important process parameters for aerobic cultivations of microorganisms and cells ar...
With the technological advances in 3D printing technology, which are associated with ever-increasing...
Biotechnological processes are a key technology in the synthesis of high-grade chemicals and pharmac...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2005.Includes...
Accurate real-time process control is necessary to increase process efficiency, and optical sensors ...
Microbioreactors (MBRs) with a volume below 1 mL are promising alternatives to established cultivati...
In recent years, microbioreactor (MBR) systems have evolved towards versatile bioprocess engineering...
This thesis presents the design, fabrication, and characterization of a batch microbioreactor with i...
Abstract Bioprocessing is of crucial importance in pharmaceutical, biofuel, food and other industri...
Abstract- Over the years, microbioreactors have been equipped with a variety of tools for online mon...
Aerobic batch cultivations of Candida utilis were carried out in two micro bioreactors with a workin...
Shaken bioreactors are widespread in the field of biotechnology. Especially, microtiter plates are i...
The rising costs of bioprocess research and development emphasize the need for high-throughput, low-...
In the manufacture of bio-therapeutics the importance of a well-known process is key for a high prod...
Abstract: Two prototype 24-unit microbioreactors are presented and reviewed for their relative merit...
Two of the most important process parameters for aerobic cultivations of microorganisms and cells ar...
With the technological advances in 3D printing technology, which are associated with ever-increasing...
Biotechnological processes are a key technology in the synthesis of high-grade chemicals and pharmac...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2005.Includes...
Accurate real-time process control is necessary to increase process efficiency, and optical sensors ...