Add to ORKGNational audienceCell cycle synchronization at a specific stage is often an essential requirement to investigate biological events and mechanisms using the large panel of molecular and cellular biology technologies. Optimization of the synchronization parameters is most of the time neglected, which could result in experimental time wasting or even in erroneous conclusions. Here we report the development of a cell cycle checkpoint-oriented simulator, based on agent-based modeling (ABM), that reproduces the dynamic behavior of a proliferating cell population and its response to checkpoint activation
A collaboration between cancer biologists and academic software engineers has been exploring the dev...
Motivation: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoi...
Due to the complexity of biological systems, simulation of biological networks is necessary but some...
Modeling and in silico simulations are of major conceptual and applicative interest in studying the ...
International audienceModeling and in silico simulations are of major conceptual and applicative int...
Abstract. In this paper we propose a new model of cell cycle simulator which will be used to analyse...
Huge amount of medical data has been generated in practical experiments which makes data analysis a ...
We present a suite of experimental data showing that cell proliferation assays, prepared using stand...
The cell cycle is one of the most fundamental biological processes by which a cell replicates its ge...
Computational models aiming at the spatio-temporal description of cancer evolution are a suitable fr...
The periodic process of cell replication by division, known as cell-cycle, is a natural phenomenon o...
Abstract The cell cycle is the process by which eukaryotic cells replicate. Yeast cells cycle async...
Motivation: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoi...
The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Com...
Cell cycle and its progression play a crucial role in the life of all living organisms, in tissues a...
A collaboration between cancer biologists and academic software engineers has been exploring the dev...
Motivation: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoi...
Due to the complexity of biological systems, simulation of biological networks is necessary but some...
Modeling and in silico simulations are of major conceptual and applicative interest in studying the ...
International audienceModeling and in silico simulations are of major conceptual and applicative int...
Abstract. In this paper we propose a new model of cell cycle simulator which will be used to analyse...
Huge amount of medical data has been generated in practical experiments which makes data analysis a ...
We present a suite of experimental data showing that cell proliferation assays, prepared using stand...
The cell cycle is one of the most fundamental biological processes by which a cell replicates its ge...
Computational models aiming at the spatio-temporal description of cancer evolution are a suitable fr...
The periodic process of cell replication by division, known as cell-cycle, is a natural phenomenon o...
Abstract The cell cycle is the process by which eukaryotic cells replicate. Yeast cells cycle async...
Motivation: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoi...
The mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Com...
Cell cycle and its progression play a crucial role in the life of all living organisms, in tissues a...
A collaboration between cancer biologists and academic software engineers has been exploring the dev...
Motivation: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoi...
Due to the complexity of biological systems, simulation of biological networks is necessary but some...