Analysis of CRISPR-induced mutations at targeted locus can be achieved by polymerase chain reaction amplification followed by parallel massive sequencing. We developed a novel algorithm, named as CRISPRpic, to analyze the sequencing reads for the CRISPR experiments via counting exact-matching and pattern-searching. Compare to the other methods based on sequence alignment, CRISPRpic provides precise mutation calling and ultrafast analysis of the sequencing results. Python script of CRISPRpic is available a
The CRISPR-Cas system biologically serves as an adaptive defense mechanism against phages. However,...
In Archaea and Bacteria, the arrays called CRISPRs for 'clustered regularly interspaced short palind...
Genome editing with the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR...
Abstract Background Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type o...
Background: CRISPR (clustered regularly interspaced short palindromic repeats) RNAs provide the spec...
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct...
Large-scale genetic screens using CRISPR/Cas9 technology have emerged as a major tool for functional...
CRISPR interference (CRISPRi) is a powerful tool to link essential and nonessential genes to specifi...
Abstract Background Genome-wide knockout studies, noncoding deletion scans, and other large-scale st...
<p>Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) technol...
Somatic mutations in cancer genomes can be caused by many different mutational processes, each of wh...
Abstract Background Genome editing by CRISPR-Cas9 technology allows large-scale screening of gene es...
Background: CRISPR-Cas9 is a revolutionary genome editing technique that allows for efficient and di...
Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification...
Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification...
The CRISPR-Cas system biologically serves as an adaptive defense mechanism against phages. However,...
In Archaea and Bacteria, the arrays called CRISPRs for 'clustered regularly interspaced short palind...
Genome editing with the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR...
Abstract Background Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type o...
Background: CRISPR (clustered regularly interspaced short palindromic repeats) RNAs provide the spec...
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct...
Large-scale genetic screens using CRISPR/Cas9 technology have emerged as a major tool for functional...
CRISPR interference (CRISPRi) is a powerful tool to link essential and nonessential genes to specifi...
Abstract Background Genome-wide knockout studies, noncoding deletion scans, and other large-scale st...
<p>Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) technol...
Somatic mutations in cancer genomes can be caused by many different mutational processes, each of wh...
Abstract Background Genome editing by CRISPR-Cas9 technology allows large-scale screening of gene es...
Background: CRISPR-Cas9 is a revolutionary genome editing technique that allows for efficient and di...
Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification...
Next-generation sequencing (NGS) has revolutionized genetics and enabled the accurate identification...
The CRISPR-Cas system biologically serves as an adaptive defense mechanism against phages. However,...
In Archaea and Bacteria, the arrays called CRISPRs for 'clustered regularly interspaced short palind...
Genome editing with the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR...