Genetic contribution of FUS to frontotemporal lobar degeneration
- Van Langenhove, T
- van der Zee, J
- Sleegers, K
- Engelborghs, S
- Vandenberghe, Rik
- Gijselinck, I
- Van den Broeck, M
- Mattheijssens, M
- Peeters, K
- De Deyn, P. P
- Cruts, M
- Van Broeckhoven, C
Publication date
February 2010
DOI Publisher
Lippincott williams & wilkins ISSN
0028-3878 Journal
issn:0028-3878Abstract
Background: Recently, the FUS gene was identified as a new causal gene for amyotrophic lateral sclerosis (ALS) in similar to 4% of patients with familial ALS. Since ALS and frontotemporal lobar degeneration (FTLD) are part of a clinical, pathologic, and genetic disease spectrum, we investigated a potential role of FUS in FTLD.status: publishe
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