Polycyclic systems containing 1,2,4-oxadiazole ring 2. 4-(1,2,4-oxadiazol-5-yl)pirrolidin-2-ones: synthesis and prediction of biological activity

A one-pot synthesis of 5-oxopyrrolidine-3-carboxylic acids, carbonyldiimidazole, and benzamidoximes leads to the formation of the novel 4-(1,2,4-oxadiazol-5-yl)pyrrolidin-2-one bicyclic systems, the structures of which have been confirmed by IR and 1H NMR methods and by liquid chromato-mass spectrometry