Add to ORKGThe recently emerged coronavirus SARS-CoV-2, the causative agent of COVID-19, is rapidly spreading in the world. The exponentially expanding threat of SARS-CoV-2 to global health highlights the urgent need for a vaccine. Herein we show the rapid development of a novel, highly efficient, and safe COVID-19 vaccine using a rabies virus-based vector that has proven to be an efficient vaccine against several emerging infectious diseases. This study reports that both a live and an inactivated rabies virus containing the SARS-CoV-2 spike S1 protein induces potent virus-neutralizing antibodies at much higher levels than seen in the sera of convalescent patients. In summary, the results provided here warrant further development of this safe and esta...
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpi...
Effective therapies are urgently needed for the SARS-CoV-2/COVID-19 pandemic. We identified panels o...
The novel coronavirus disease (COVID-19) pandemic continues to be a worldwide threat and effective a...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent coronavirus that has cau...
An important effort has been performed after the emergence of severe acute respiratory syndrome (SAR...
© 2017 American Society for Microbiology. Middle East respiratory syndrome coronavirus (MERS-CoV) em...
Introduction: Until the beginning of the 21st century human coronaviruses were known as the cause of...
Immunization with a killed or inactivated viral vaccine provides significant protection in animals a...
A group of Jefferson viral vaccine researchers led by Jefferson Vaccine Center (JVC) director and pr...
The COVID-19 pandemic is a major threat to global health1 for which there are limited medical counte...
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) arose as a novel virus in Wuhan China i...
The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respirator...
Coronavirus Disease 2019 (COVID-19), caused by infection with Severe Acute Respiratory Syndrome Coro...
The inactivated rabies vaccine has been safely administered for decades. An immunogenic inactivated ...
Background: Due to the lack of protective immunity of humans towards the newly emerged SARS-CoV-2, t...
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpi...
Effective therapies are urgently needed for the SARS-CoV-2/COVID-19 pandemic. We identified panels o...
The novel coronavirus disease (COVID-19) pandemic continues to be a worldwide threat and effective a...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent coronavirus that has cau...
An important effort has been performed after the emergence of severe acute respiratory syndrome (SAR...
© 2017 American Society for Microbiology. Middle East respiratory syndrome coronavirus (MERS-CoV) em...
Introduction: Until the beginning of the 21st century human coronaviruses were known as the cause of...
Immunization with a killed or inactivated viral vaccine provides significant protection in animals a...
A group of Jefferson viral vaccine researchers led by Jefferson Vaccine Center (JVC) director and pr...
The COVID-19 pandemic is a major threat to global health1 for which there are limited medical counte...
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) arose as a novel virus in Wuhan China i...
The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respirator...
Coronavirus Disease 2019 (COVID-19), caused by infection with Severe Acute Respiratory Syndrome Coro...
The inactivated rabies vaccine has been safely administered for decades. An immunogenic inactivated ...
Background: Due to the lack of protective immunity of humans towards the newly emerged SARS-CoV-2, t...
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpi...
Effective therapies are urgently needed for the SARS-CoV-2/COVID-19 pandemic. We identified panels o...
The novel coronavirus disease (COVID-19) pandemic continues to be a worldwide threat and effective a...