Can we design efficient algorithms for finding fast algorithms? This question is captured by various circuit minimization problems, and algorithms for the corresponding tasks have significant practical applications. Following the work of Cook and Levin in the early 1970s, a central question is whether minimizing the circuit size of an explicitly given function is NP-complete. While this is known to hold in restricted models such as DNFs, making progress with respect to more expressive classes of circuits has been elusive. In this work, we establish the first NP-hardness result for circuit minimization of total functions in the setting of general (unrestricted) Boolean circuits. More precisely, we show that computing the minimum circuit siz...