Vitamin D supplementation as a rational pharmacological approach in the covid-19 pandemic
- Ferder, Leon Fernando
- Martín Giménez, Virna Margarita
- Inserra, Felipe
- Tajer, Carlos Daniel
- Antonietti, Laura
- Mariani, Javier
- Manucha, Walter Ariel Fernando
DOIAbstract
The COVID-19 pandemic has reached most of the countries worldwide causing death, which often results from an inflammatory storm associated with severe acute respiratory syndrome (SARS). This has prompted researchers to seek specific novel and definitive treatments urgently. In this context, it is interesting to evaluate the preventive and therapeutic effects of existing pharmacological agents that could be useful. In this regard, vitamin D supplementation, particularly in individuals likely to be deficient, may be a promising option. Vitamin D is a hormone that modulates many of the same inflammatory and oxidative signaling pathways triggered during COVID-19. For example, vitamin D suppresses the actions of the renin-angiotensin system, whi...
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