Influence of comorbidity and cognitive status on instrumental activities of daily living in amnestic mild cognitive impairment: Results from the ReGA1 project
- Mariani E.
- Monastero R.
- Ercolani S.
- Rinaldi P.
- Mangialasche F.
- Costanzi E.
- Vitale D. F.
- Senin U.
- Mecocci P.
- Gabelli C.
- Codemo A.
- Marinelli K.
- Capurso A.
- Cucinotta D.
- Reggiani A.
- Ellena L.
- Zanetti O.
- Putzu P.
- Del Prete M.
- Spaccamento S.
- Abate G.
- Di Iorio A.
- Cester A.
- Formilan M.
- Busonera F.
- Anzivino F.
- Masotti G.
- Cavallini C.
- Mossello E.
- Odetti P.
- Cataldi A. G.
- Pippi M.
- Estraneo A.
- Sica G.
- Renna S.
- Nicita-Mauro V.
- Basile G.
- Salvioli G.
- Mussi C.
- Ascari S.
- Casale R.
- Frazzitta G.
- Scognamiglio M.
- Di Palma A.
- Rengo F.
- Canonico V.
- Fortunato F.
- Enzi G.
- Giordano M.
- Vitrano Catania T.
- Ferrari E.
- Cuzzoni G.
- Del Re M. L.
- Guizzardi G.
- Biagini C.
- Bavazzano A.
- Ferrari A.
- Dallari A.
- Carbonin P.
- Bernabei R.
- Silveri M. C.
- Bartorelli L.
- Gandolfi B.
- Cerqua R.
- Pilotto A.
- Cascavilla L.
- Chiaranti A.
- Marinelli M.
- Tripi G.
- Gallucci M.
- Marchetti C.
- Masiello V.
- Sacco D.
- Ricci G.
DOIAbstract
Objectives: To investigate whether amnestic mild cognitive impairment (aMCI) is characterised by restriction in instrumental activities of daily living (IADL). Further, to examine the role of comorbidity and cognitive performance on IADL changes in aMCI subjects. Methods: The study included 132 subjects with aMCI and 249 subjects with no cognitive impairment (NCI), consecutively enrolled as outpatients in a multicentric Italian clinical-based study, the ReGAl Project. All subjects underwent a comprehensive evaluation including clinical examination, laboratory screening, neuroimaging and cognitive and behavioral assessments. Functional status was evaluated by the Lawton's Instrumental Activities of Daily Living (IADL) scale. Comorbidity was ...
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