Gd2O3, SiO2-Gd2O3 and SiO2-MnO2 nanoparticles as potential MRI contrast agents
- Myshkina, A. V.
- Bazhukova, I. N.
- Zlygosteva, O. A.
- Byzov, I. V.
- Kasyanova, V. V.
- Sokovnin, S. Y.
- Ilves, V. G.
DOIAbstract
Gd2O3, SiO2-Gd2O3 and SiO2-MnO2 nanoparticles were produced by the method of pulsed electron evaporation of oxide targets with condensation of the vapors in a vacuum. These materials are considered as probable contrast agents for magnetic resonance imaging (MRI). The Gd2O3 nanoparticles exhibit a rather high r1 and r2 relaxivities. These results point to the potential of using nanocrystals for MRI diagnosis. The mesoporous nanostructures SiO2-Gd2O3 and SiO2-MnO2 could be considered as multimodal theranostic agents. © 2020 IOP Publishing Ltd
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