Add to ORKGBackground and aims: Pancreatic β-cell failure is central in the pathogenesis of diabetes. In vitro differentiation of human induced pluripotent stem cells (iPSCs) into β-cells represents a novel cell source for diabetes research. Here we differentiated iPSC-β-cells and tested their function in vitro and in vivo in humanized mice [...
Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered...
Summary: Recent advances in human pluripotent stem cell (hPSC) differentiation protocols have genera...
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) a...
In vitro differentiation of human induced pluripotent stem cells (iPSCs) into beta cells represents ...
AIMS: New sources of insulin-secreting cells are strongly required for the cure of diabetes. Recent...
The lack or dysfunction of insulin-producing beta-cells is the cause of all forms of diabetes. In vi...
Type 1 diabetes is characterized by autoimmune destruction of β cells located in pancreatic islets. ...
BACKGROUND New sources of insulin-secreting cells are strongly required for the cure of diabetes. Re...
SummaryThe generation of insulin-producing pancreatic β cells from stem cells in vitro would provide...
Type 2 diabetes, characterized by dysfunction of pancreatic β-cells and insulin resistance in periph...
Abstract Recent advances in the expansion and directed pancreatogenic differentiation of human pluri...
Diabetes mellitus is characterized by elevated levels of blood glucose and is ultimately caused by i...
Adult human pancreatic beta cells are the "gold standard" for studies on diabetes pathogenesis, but ...
AbstractThe potential of pluripotent human cells, such as human embryonic stem cells (hESCs) and ind...
Human pluripotent stem cells can in principle be used as a source of any differentiated cell type fo...
Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered...
Summary: Recent advances in human pluripotent stem cell (hPSC) differentiation protocols have genera...
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) a...
In vitro differentiation of human induced pluripotent stem cells (iPSCs) into beta cells represents ...
AIMS: New sources of insulin-secreting cells are strongly required for the cure of diabetes. Recent...
The lack or dysfunction of insulin-producing beta-cells is the cause of all forms of diabetes. In vi...
Type 1 diabetes is characterized by autoimmune destruction of β cells located in pancreatic islets. ...
BACKGROUND New sources of insulin-secreting cells are strongly required for the cure of diabetes. Re...
SummaryThe generation of insulin-producing pancreatic β cells from stem cells in vitro would provide...
Type 2 diabetes, characterized by dysfunction of pancreatic β-cells and insulin resistance in periph...
Abstract Recent advances in the expansion and directed pancreatogenic differentiation of human pluri...
Diabetes mellitus is characterized by elevated levels of blood glucose and is ultimately caused by i...
Adult human pancreatic beta cells are the "gold standard" for studies on diabetes pathogenesis, but ...
AbstractThe potential of pluripotent human cells, such as human embryonic stem cells (hESCs) and ind...
Human pluripotent stem cells can in principle be used as a source of any differentiated cell type fo...
Abstract Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered...
Summary: Recent advances in human pluripotent stem cell (hPSC) differentiation protocols have genera...
The directed differentiation of human pluripotent stem cells, such as embryonic stem cells (hESCs) a...