Microbial signatures in metabolic tissues: a novel paradigm for obesity and diabetes?

Visceral fat accumulation is considered one of the most important risk factors for the development of type 2 diabetes. Although the molecular mechanisms linking visceral fat accretion to impaired glucose metabolism are not yet fully elucidated, one commonly accepted trigger is chronic low-grade inflammation in the visceral fat and metabolic organs, such as the liver and muscles, in people with diabetes and obesity. […