In many types of cancer, tumors metastasize through the lymphatic system to draining lymph nodes. These sentinel lymph nodes have gained increased attention as a prognostic indicator for the severity of the disease, leading to the sentinel lymph node mapping and biopsy procedure to be accepted as standard-of-care for breast cancer and melanoma. However, many limitations exist with this procedure resulting in high false negative rates. In this review we highlight the new advances in the understanding of the molecular mechanisms of lymphangiogenesis and tumor metastasis that may lead to improved strategies in the detection of the sentinel lymph nodes and therapeutic interventions to prevent further tumor spread. In addition, advances in imagi...
Introduction: The introduction of lymphoscintigraphy and sentinel node biopsy (SNB) has revealed pre...
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal dise...
Tumor lymphangiogenesis is accompanied by a higher incidence of sentinel lymph node metastasis and s...
Abstract Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune modulati...
Metastasis the spread of cancer cells to distant organs, is the main cause of death for cancer patie...
Malignant tumors of ectodermal or endodermal origin may metastasize to the sentinel lymph node, the ...
[[abstract]]Metastasis is a major cause of death in patients with cancer. The two main routes for ca...
Knowledge on lymph node metastases is crucial for the prognosis and treatment of prostate cancer pat...
Knowledge on lymph node metastases is crucial for the prognosis and treatment of prostate cancer pat...
Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal ...
The lymphatic system serves as the primary route for the metastasis of many cancers and the extent o...
Abstract: The extent of lymph node (LN) metas-tasis is a major determinant for the staging and the p...
Regional lymph node metastasis is a common event in solid tumors and is considered a marker for diss...
Prostate is cancer is the most commonly diagnosed cancer in men worldwide and the second biggest kil...
Breast cancer is one of the most important causes of premature mortality among women and it is one o...
Introduction: The introduction of lymphoscintigraphy and sentinel node biopsy (SNB) has revealed pre...
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal dise...
Tumor lymphangiogenesis is accompanied by a higher incidence of sentinel lymph node metastasis and s...
Abstract Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune modulati...
Metastasis the spread of cancer cells to distant organs, is the main cause of death for cancer patie...
Malignant tumors of ectodermal or endodermal origin may metastasize to the sentinel lymph node, the ...
[[abstract]]Metastasis is a major cause of death in patients with cancer. The two main routes for ca...
Knowledge on lymph node metastases is crucial for the prognosis and treatment of prostate cancer pat...
Knowledge on lymph node metastases is crucial for the prognosis and treatment of prostate cancer pat...
Lymphangiogenesis remains a fascinating biological process that plays a crucial role in both normal ...
The lymphatic system serves as the primary route for the metastasis of many cancers and the extent o...
Abstract: The extent of lymph node (LN) metas-tasis is a major determinant for the staging and the p...
Regional lymph node metastasis is a common event in solid tumors and is considered a marker for diss...
Prostate is cancer is the most commonly diagnosed cancer in men worldwide and the second biggest kil...
Breast cancer is one of the most important causes of premature mortality among women and it is one o...
Introduction: The introduction of lymphoscintigraphy and sentinel node biopsy (SNB) has revealed pre...
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal dise...
Tumor lymphangiogenesis is accompanied by a higher incidence of sentinel lymph node metastasis and s...