Antioxidant and immunoregulatory activity of polysaccharides from adzuki beans (Vigna angularis)

peer reviewedWater-extractable and alkali-extractable polysaccharides from the seed of adzuki beans and their three polysaccharide sub-fractions were isolated and purified by anion-exchange and gel filtration chromatography. AWP-1 and AWP-2 were composed of Rha, Ara, Man, Gal and Glu. AAP-1 was composed of Rha, Ara, Man, Gal and GalA. The antioxidant and immunoregulatory activities of the polysaccharides were evaluated. The results indicated that AWP-1, AWP-2, and AAP-1 had significant antioxidant and immunoregulatory activities. The results suggest that AWP-1, AWP-2, and AAP-1 have therapeutic implications in the treatment of inflammation and inflammatory-related disease. © 2015 Elsevier Ltd.HongKong, Macao and Taiwan Science & Technology Cooperation Program of China (2014DFT30280, 2013DFT3050); Special fund for Agro-scientific Research in the Public Interest (201403063); Earmarked fund for China Agriculture Research System Modern Agro-industry Technology (CYTX-014); Agricultural Science and Technology Program for Innovation Team on Identification and Excavation of Elite Crop Germplasm, CAAS