BACKGROUND: In the near future, adult porcine islets of Langerhans appear as an unlimited source of insulin-producing cells which could play a major role for treating diabetes mellitus. There is, however, an obvious lack of pre-clinical results and data in the pig-to-primate model. One of the main hurdles of this model is certainly related to the difficulty of reproducing regularly successful porcine islet isolation. This experimental work was designed to provide guidelines applicable in pig pancreas procurement and islet isolation for successful islet xenotransplantation into primates. METHODS: Pancreases were harvested from adult Belgium Landrace pigs (n = 79) in a single centre. The impact on islet yield of (1) pancreas procurement (bloo...
BACKGROUND: Porcine pancreas is a potential source of material for islet xenotransplantation. Howeve...
Allogeneic islet transplantation has proven difficult because organ shortages are recurrent, several...
BackgroundPorcine islet xenotransplantation has been demonstrated in many animal studies to cure exp...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
Pig islets are considered the best alternative to human islets in the treatment of insulin-dependent...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
Allogeneic islet transplantation faces difficulties because (1) organ shortage is recurrent; (2) sev...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
BACKGROUND: Metabolic compatibility between donor and recipient species is an important matter for p...
PURPOSE OF REVIEW: Allogeneic islet transplantation faces difficulties because organ shortage is rec...
Diabetes mellitus is increasing worldwide. Type 1 diabetes can be treated successfully by islet allo...
BACKGROUND: Islet cell transplantation is a novel therapeutic modality for the cure of diabetes. Pig...
Diabetes is a major health problem worldwide, and there is substantial interest in developing xenoge...
Islet allotransplantation has been shown to have potential as a treatment for type 1 diabetic patien...
Isolement d'îlots de Langerhans porcins: évaluation de la fonction in vitro et in vivo FOURNIER...
BACKGROUND: Porcine pancreas is a potential source of material for islet xenotransplantation. Howeve...
Allogeneic islet transplantation has proven difficult because organ shortages are recurrent, several...
BackgroundPorcine islet xenotransplantation has been demonstrated in many animal studies to cure exp...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
Pig islets are considered the best alternative to human islets in the treatment of insulin-dependent...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
Allogeneic islet transplantation faces difficulties because (1) organ shortage is recurrent; (2) sev...
Allogeneic islet transplantation faces serious difficulties since organ shortage is recurrent and th...
BACKGROUND: Metabolic compatibility between donor and recipient species is an important matter for p...
PURPOSE OF REVIEW: Allogeneic islet transplantation faces difficulties because organ shortage is rec...
Diabetes mellitus is increasing worldwide. Type 1 diabetes can be treated successfully by islet allo...
BACKGROUND: Islet cell transplantation is a novel therapeutic modality for the cure of diabetes. Pig...
Diabetes is a major health problem worldwide, and there is substantial interest in developing xenoge...
Islet allotransplantation has been shown to have potential as a treatment for type 1 diabetic patien...
Isolement d'îlots de Langerhans porcins: évaluation de la fonction in vitro et in vivo FOURNIER...
BACKGROUND: Porcine pancreas is a potential source of material for islet xenotransplantation. Howeve...
Allogeneic islet transplantation has proven difficult because organ shortages are recurrent, several...
BackgroundPorcine islet xenotransplantation has been demonstrated in many animal studies to cure exp...