Peroxins 5 and 7 are receptors for protein import into the peroxisomal matrix. We studied the involvement of these peroxins in the biogenesis of glycosomes in the protozoan parasite Trypanosoma brucei. Glycosomes are peroxisome-like organelles in which a major part of the glycolytic pathway is sequestered. We here report the characterization of the T. brucei homologue of PEX7 and provide several data strongly suggesting that it can bind to PEX5. Depletion of PEX5 or PEX7 by RNA interference had a severe effect on the growth of both the bloodstream-form of the parasite, that relies entirely on glycolysis for its ATP supply, and the procyclic form representative of the parasite living in the tsetse-fly midgut and in which also other metabolic...
Peroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in import of ...
Trypanosomatids contain peroxisome-like organelles called glycosomes. Peroxisomal biogenesis involve...
AbstractPeroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in im...
AbstractPeroxins 5 and 7 are receptors for protein import into the peroxisomal matrix. We studied th...
It has been shown previously in various organisms that the peroxin PEX14 is a component of a docking...
Protozoan Kinetoplastida such as the pathogenic trypanosomes compartmentalize several important meta...
AbstractProtozoan Kinetoplastida such as the pathogenic trypanosomes compartmentalize several import...
Glycolysis in kinetoplastid protists such as Trypanosoma brucei is compartmentalized in peroxisome-l...
Glycosome biogenesis in trypanosomatids occurs via a process that is homologous to peroxisome biogen...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
Glycosomes are peroxisome-like organelles essential for trypanosomatid parasites. Glycosome biogenes...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
AbstractProtozoan parasites of the family Trypanosomatidae infect humans as well as livestock causin...
AbstractTrypanosomatids contain peroxisome-like organelles called glycosomes. Peroxisomal biogenesis...
Peroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in import of ...
Trypanosomatids contain peroxisome-like organelles called glycosomes. Peroxisomal biogenesis involve...
AbstractPeroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in im...
AbstractPeroxins 5 and 7 are receptors for protein import into the peroxisomal matrix. We studied th...
It has been shown previously in various organisms that the peroxin PEX14 is a component of a docking...
Protozoan Kinetoplastida such as the pathogenic trypanosomes compartmentalize several important meta...
AbstractProtozoan Kinetoplastida such as the pathogenic trypanosomes compartmentalize several import...
Glycolysis in kinetoplastid protists such as Trypanosoma brucei is compartmentalized in peroxisome-l...
Glycosome biogenesis in trypanosomatids occurs via a process that is homologous to peroxisome biogen...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
Glycosomes are peroxisome-like organelles essential for trypanosomatid parasites. Glycosome biogenes...
Kinetoplastid organisms, such as the protozoan parasite Trypanosoma brucei, compartmentalise several...
AbstractProtozoan parasites of the family Trypanosomatidae infect humans as well as livestock causin...
AbstractTrypanosomatids contain peroxisome-like organelles called glycosomes. Peroxisomal biogenesis...
Peroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in import of ...
Trypanosomatids contain peroxisome-like organelles called glycosomes. Peroxisomal biogenesis involve...
AbstractPeroxin 13 (PEX13) is one of the components of a peroxisomal membrane complex involved in im...