Development of pathology varies widely between different strains of mice after intracerebral inoculation with the so-called 'docile' isolate of Lymphocytic Choriomeningitis (LCM) virus. The C3HeB/FeJ and B10. Br/SgSnJ mouse strains have been of special interest because they display autoimmune haemolytic anaemia with varying degrees of apparent immunological involvement. In this report, we examined the role of CD4+ T helper cells in this autoimmune response by treating mice with the CD4-specific GK1.5 monoclonal antibody. We also determined if polyclonal activation of B lymphocytes, induced either by LCM virus or by lactate dehydrogenase-elevating virus, another well known B cell activator, correlated with the development of anaemia in these...
NZB mice develop autoimmune haemolytic anaemia (AIHA) as a result of the spontaneous production of R...
Infections with a variety of viruses (lymphocytic choriomeningitis (LCMV), murine cytomegalovirus, P...
Hypergammaglobulinemia and production of autoantibodies occur during many viral infections, and stud...
The effect of LCMV on CD4+ T lymphocytes was analyzed in C3HeB/FeJ mice after infection with the Doc...
C3HeB/FeJ mice infected with the docile strain of lymphocytic choriomeningitis virus (LCMV-d) develo...
Mice infected intracerebrally with lymphocytic choriomeningitis virus (LCM virus) develop a characte...
The development of autoimmunity was investigated in BALB/c and C58 mice infected with lactate dehydr...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
As shown previously, after inoculation into the footpad of a mouse the lymphocytic choriomeningitis ...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
The infectivity of blood and lymphoid organs of mice persistently infected with lymphocytic choriome...
A search was made in LCM virus-immune mice for virus-specific antibodies. With the help of an L-cell...
Lactate dehydrogenase-elevating virus (LDV) produces a permanent infection in mice with a B-lymphocy...
Strong enhancement of the pathogenicity of an antierythrocyte monoclonal antibody was observed after...
Using the model of lymphocytic choriomeningitis virus (LCMV) in mice we have first investigated anti...
NZB mice develop autoimmune haemolytic anaemia (AIHA) as a result of the spontaneous production of R...
Infections with a variety of viruses (lymphocytic choriomeningitis (LCMV), murine cytomegalovirus, P...
Hypergammaglobulinemia and production of autoantibodies occur during many viral infections, and stud...
The effect of LCMV on CD4+ T lymphocytes was analyzed in C3HeB/FeJ mice after infection with the Doc...
C3HeB/FeJ mice infected with the docile strain of lymphocytic choriomeningitis virus (LCMV-d) develo...
Mice infected intracerebrally with lymphocytic choriomeningitis virus (LCM virus) develop a characte...
The development of autoimmunity was investigated in BALB/c and C58 mice infected with lactate dehydr...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
As shown previously, after inoculation into the footpad of a mouse the lymphocytic choriomeningitis ...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
The infectivity of blood and lymphoid organs of mice persistently infected with lymphocytic choriome...
A search was made in LCM virus-immune mice for virus-specific antibodies. With the help of an L-cell...
Lactate dehydrogenase-elevating virus (LDV) produces a permanent infection in mice with a B-lymphocy...
Strong enhancement of the pathogenicity of an antierythrocyte monoclonal antibody was observed after...
Using the model of lymphocytic choriomeningitis virus (LCMV) in mice we have first investigated anti...
NZB mice develop autoimmune haemolytic anaemia (AIHA) as a result of the spontaneous production of R...
Infections with a variety of viruses (lymphocytic choriomeningitis (LCMV), murine cytomegalovirus, P...
Hypergammaglobulinemia and production of autoantibodies occur during many viral infections, and stud...