Improvement in quality of life (QoL) following treatment for alcohol dependence with acamprosate and psychosocial support.

The impact of disease on health-related quality of life is now well recognized, as is the importance of this variable as a measure of treatment efficacy. Methods: Patients from five European countries were enrolled in an open, multicenter, prospective study designed to observe outcome in dependent drinkers treated for 6 months with acamprosate and psychosocial support. Version 1 of the 36-item Short Form Health Profile (SF-36v1) questionnaire was administered at inclusion and at 3 and 6 months. Responses were described as handicaps compared with an appropriately matched, healthy reference population. One-way fixed ANOVA and simultaneous stepwise linear regression analysis were used to identify potential predictors of quality of life at baseline and after treatment.Nous investiguons la relation entre la sévérité de l'alcoolo-dépendance et la qualité de vie et étudions l'influence de l'interruption de consommation via un traitement pharmacologique