Vascular supply is an obvious requirement for all organs. In addition to oxygen and nutrients, blood flow also transports essential trace elements. Iodine, which is a key element in thyroid hormone synthesis, is one of them. An inverse relationship exists between the expansion of the thyroid microvasculature and the local availability of iodine. This microvascular trace element-dependent regulation is unique and contributes to keep steady the iodide delivery to the thyroid. Signals involved in this regulation, such as VEGF-A, originate from thyrocytes as early TSH-independent responses to iodide scarcity. The question raised in this paper is how thyrocytes, facing an acute drop in intracellular stores of iodine; generate angiogenic signals ...
Artículo de publicación ISINa+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, ...
The fundamental role of the thyroid gland is to ensure the biosynthesis of thyroid hormones whose pr...
In animals, as well as in humans, the thyroid gland is made of active follicles, with cuboidal cells...
Expansion of the thyroid microvasculature is the earliest event during goiter formation, always occu...
Background: In the thyroid, iodine deficiency (ID) induces angiogenesis via a tightly controlled rea...
Iodide is a micronutrient essential for thyroid hormone production. The uptake and metabolism of iod...
Despite efforts to optimize iodine supply in iodine deficient countries, iodine deficiency (ID) rema...
Iodine is an essential element required for diverse physiological functions, including thyroid hormo...
In thyrocytes, cell polarity is of crucial importance for proper thyroid function. Many intrinsic me...
Iodine deficiency (ID), which affects almost two billion people worldwide, is associated with breast...
The thyroid angio-follicular units early react to iodine deficiency (ID) by promoting an increase of...
Iodine deficiency (ID) induces microvascular changes in the thyroid gland via a TSH-independent reac...
Vasoactive and angiogenic factors are involved in the autocrine/paracrine thyroid regulation of micr...
International audienceNa+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the f...
Placenta growth factor (PlGF) and vascular endothelial growth factor (VEGF) represent two closely re...
Artículo de publicación ISINa+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, ...
The fundamental role of the thyroid gland is to ensure the biosynthesis of thyroid hormones whose pr...
In animals, as well as in humans, the thyroid gland is made of active follicles, with cuboidal cells...
Expansion of the thyroid microvasculature is the earliest event during goiter formation, always occu...
Background: In the thyroid, iodine deficiency (ID) induces angiogenesis via a tightly controlled rea...
Iodide is a micronutrient essential for thyroid hormone production. The uptake and metabolism of iod...
Despite efforts to optimize iodine supply in iodine deficient countries, iodine deficiency (ID) rema...
Iodine is an essential element required for diverse physiological functions, including thyroid hormo...
In thyrocytes, cell polarity is of crucial importance for proper thyroid function. Many intrinsic me...
Iodine deficiency (ID), which affects almost two billion people worldwide, is associated with breast...
The thyroid angio-follicular units early react to iodine deficiency (ID) by promoting an increase of...
Iodine deficiency (ID) induces microvascular changes in the thyroid gland via a TSH-independent reac...
Vasoactive and angiogenic factors are involved in the autocrine/paracrine thyroid regulation of micr...
International audienceNa+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the f...
Placenta growth factor (PlGF) and vascular endothelial growth factor (VEGF) represent two closely re...
Artículo de publicación ISINa+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, ...
The fundamental role of the thyroid gland is to ensure the biosynthesis of thyroid hormones whose pr...
In animals, as well as in humans, the thyroid gland is made of active follicles, with cuboidal cells...