Add to ORKGThe extent of physico-chemical changes induced by irradiation of cefazolin sodium was investigated. The methods used were potency determination, impurity profile, colour measurements and pH measurements. The potency of irradiated samples at 25 kGy was 4+/-2% lower than that of the non irradiated ones. The total amount of related substances increased from 0.72+/-0.01% in the non irradiated samples to 4.9+/-0.7% in the samples irradiated at 25 kGy. Most of the peaks showed trace amounts (<0.01%), the largest one represented 1.2+/-0.5% of the total related substances. Only two peaks were identified by chromatography: the methyl-1,2,3-thiazol-2 thiol-5 and the 7-aminocephalosporanic acid. The latter related substance is only produced by the irr...
Purpose: The aim of the present study was to establish the inherent stability of cefazolin through s...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...
The extent of physico-chemical changes induced by irradiation of cefazolin sodium was investigated. ...
In this paper, the products studied are cefazolin, glucagon and dobutamine HCl. The radioresistance ...
Three antibiotics sulfafurazole (SFZ), sulfamethoxazole (SMZ) and sulfacetamide sodium (SSA-Na) belo...
The effects of radiosterilization on the purity profile of cefotaxime were evaluated by a liquid chr...
In this work we studied qualitative methods for analysis and identification of cefazolin sodium, β-l...
In the present study, the effects of different doses of gamma radiation on two different members of ...
Cefazolin is a semisynthetic broad-spectrum first-generation cephalosporin antibiotic useful for the...
In many countries, high rates of mortality and morbidity from infectious diseases represent high soc...
Two unknown impurities were detected in the cefazolin sodium bulk drug substance using gradient reve...
Background: The radiation sterilization is one of the best methods for sterilizing vulnerable degrad...
A reversed-phase high performance liquid chromatography method was validated for the determination o...
Cefazolin sodium is a broad-spectrum first-generation cephalosporin antibiotic useful for the treatm...
Purpose: The aim of the present study was to establish the inherent stability of cefazolin through s...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...
The extent of physico-chemical changes induced by irradiation of cefazolin sodium was investigated. ...
In this paper, the products studied are cefazolin, glucagon and dobutamine HCl. The radioresistance ...
Three antibiotics sulfafurazole (SFZ), sulfamethoxazole (SMZ) and sulfacetamide sodium (SSA-Na) belo...
The effects of radiosterilization on the purity profile of cefotaxime were evaluated by a liquid chr...
In this work we studied qualitative methods for analysis and identification of cefazolin sodium, β-l...
In the present study, the effects of different doses of gamma radiation on two different members of ...
Cefazolin is a semisynthetic broad-spectrum first-generation cephalosporin antibiotic useful for the...
In many countries, high rates of mortality and morbidity from infectious diseases represent high soc...
Two unknown impurities were detected in the cefazolin sodium bulk drug substance using gradient reve...
Background: The radiation sterilization is one of the best methods for sterilizing vulnerable degrad...
A reversed-phase high performance liquid chromatography method was validated for the determination o...
Cefazolin sodium is a broad-spectrum first-generation cephalosporin antibiotic useful for the treatm...
Purpose: The aim of the present study was to establish the inherent stability of cefazolin through s...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...
Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM...