T cell defined antigens have now been characterized in a large variety of tumor types, in both mice and humans. An increasing number of these antigens appear to result from tumor-specific mutations, and some of these mutations may be implicated in oncogenesis. The priority is now to demonstrate that immunization against some of these antigens is clinically valuable for antitumor therapy, and the first results of clinical pilot studies are now emerging
Prevention of cancer through the activation of the immune system has been explored in recent years i...
Cancer cells bear markers (antigens) that identify them to the immune system, thereby making them ta...
Cytolytic T-lymphocytes (CTLs) mediate tumour rejection in several animal models. In humans, presumi...
A series of tumor cell antigens that are recognized by cytolytic T lymphocytes has been characterize...
Tumor immunology has come into the limelight since the realization that antitumor cytotoxic T lympho...
Several tumor antigens recognized by T lymphocytes have now been identified at the molecular level. ...
Several independent groups have developed methods aimed at identifying antigens that are expressed o...
In the last five years, knowledge of human tumor antigens recognized by autologous cytolytic T lymph...
Cancer cells bear markers (antigens) that identify them to the immune system. These antigens can be ...
T cell-based cancer immunotherapy relies on advancements made over the last 20 years on the molecula...
Antitumor immunity was first suggested in animals that reject tumor challenge after immunization wit...
The identification and characterization of tumor antigens as well as the expansion of knowledge on t...
peer reviewedThe nature of the tumor antigens that are detectable by T cells remains unclear. In mel...
T cells, as an essential part of the adaptive immune system, play crucial role in eradication of tum...
Tumour immunology encompasses a broad array of biological phenomena including interactions between n...
Prevention of cancer through the activation of the immune system has been explored in recent years i...
Cancer cells bear markers (antigens) that identify them to the immune system, thereby making them ta...
Cytolytic T-lymphocytes (CTLs) mediate tumour rejection in several animal models. In humans, presumi...
A series of tumor cell antigens that are recognized by cytolytic T lymphocytes has been characterize...
Tumor immunology has come into the limelight since the realization that antitumor cytotoxic T lympho...
Several tumor antigens recognized by T lymphocytes have now been identified at the molecular level. ...
Several independent groups have developed methods aimed at identifying antigens that are expressed o...
In the last five years, knowledge of human tumor antigens recognized by autologous cytolytic T lymph...
Cancer cells bear markers (antigens) that identify them to the immune system. These antigens can be ...
T cell-based cancer immunotherapy relies on advancements made over the last 20 years on the molecula...
Antitumor immunity was first suggested in animals that reject tumor challenge after immunization wit...
The identification and characterization of tumor antigens as well as the expansion of knowledge on t...
peer reviewedThe nature of the tumor antigens that are detectable by T cells remains unclear. In mel...
T cells, as an essential part of the adaptive immune system, play crucial role in eradication of tum...
Tumour immunology encompasses a broad array of biological phenomena including interactions between n...
Prevention of cancer through the activation of the immune system has been explored in recent years i...
Cancer cells bear markers (antigens) that identify them to the immune system, thereby making them ta...
Cytolytic T-lymphocytes (CTLs) mediate tumour rejection in several animal models. In humans, presumi...
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