In view of the fast-growing industrial applications of engineered nanomaterials (ENMs), the evaluation of their genotoxic potential and of their mode of action is a necessity to conduct adequate hazard/risk assessment and to produce safer and sustainable ENMs. This review aims at: (i) Providing an evaluation of in vitro and in vivo genotoxicity data available for ENMs, and (ii) proposing minimal criteria for conducting nano-genotoxicity assays. The possible modes of action of ENM (i.e., generation of reactive oxygen species (ROS) and mechanical interference with cellular components) and the potential cellular targets are discussed. The available studies are evaluated on the basis of specific quality criteria after categorisation according t...
The manufactured nanomaterials (NMs) have specific physicochemical properties that confer unique mec...
Nanomaterials offer the potential for positive technological impact in a variety of industries. The ...
There is a pressing requirement to define a hazard identification and risk management strategy for n...
Changes in the genetic material can lead to serious human health defects, as mutations in somatic ce...
Engineered nanomaterials (ENMs) possess unique biological, physical and chemical properties due to t...
Changes in the genetic material can lead to serious human health defects, as mutations in somatic ce...
Nanomaterials (NMs) are widely used in a diversity of consumer products, despite uncertainties surro...
Abstract Background It is well established that toxicological evaluation of engineered nanomaterials...
For safety assessment of nanomaterials (NMs), in vitro genotoxicity data based on welldesigned exper...
ABSTRACT: This study reports a comparative and mechanistic genotoxicity assessment of four engineere...
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials pro...
Fundamental and application-driven research in nanotechnology is expected to boost nanoscience and i...
BACKGROUND: It is well established that toxicological evaluation of engineered nanomaterials (NMs) i...
Increased engineered nanomaterial (ENM) production and incorporation in consumer and biomedical prod...
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or...
The manufactured nanomaterials (NMs) have specific physicochemical properties that confer unique mec...
Nanomaterials offer the potential for positive technological impact in a variety of industries. The ...
There is a pressing requirement to define a hazard identification and risk management strategy for n...
Changes in the genetic material can lead to serious human health defects, as mutations in somatic ce...
Engineered nanomaterials (ENMs) possess unique biological, physical and chemical properties due to t...
Changes in the genetic material can lead to serious human health defects, as mutations in somatic ce...
Nanomaterials (NMs) are widely used in a diversity of consumer products, despite uncertainties surro...
Abstract Background It is well established that toxicological evaluation of engineered nanomaterials...
For safety assessment of nanomaterials (NMs), in vitro genotoxicity data based on welldesigned exper...
ABSTRACT: This study reports a comparative and mechanistic genotoxicity assessment of four engineere...
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials pro...
Fundamental and application-driven research in nanotechnology is expected to boost nanoscience and i...
BACKGROUND: It is well established that toxicological evaluation of engineered nanomaterials (NMs) i...
Increased engineered nanomaterial (ENM) production and incorporation in consumer and biomedical prod...
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or...
The manufactured nanomaterials (NMs) have specific physicochemical properties that confer unique mec...
Nanomaterials offer the potential for positive technological impact in a variety of industries. The ...
There is a pressing requirement to define a hazard identification and risk management strategy for n...