The damaged septohippocampal pathway was utilized to study the axonal regeneration of injured neurons. Semipermeable tubes, 2-mm long, were placed in the axis of the transected septohippocampal pathway of adult rats. In a first series of experiments, empty tubes were implanted. Even six weeks after the operation, no regenerated axons were observed in the conduit. In a second series of experiments, in order to validate our approach, segments of pre-degenerated sciatic nerves were introduced into the tubes. Under these experimental conditions, acetylcholinesterase (AChE)-containing regenerated axonal processes were detected in the grafted sciatic nerves. Glial fibrillary acidic protein (GFAP)-immunodetection showed that astroglial cells and a...
Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative ...
The present work elucidates the connectivity of adult retinal ganglion cell axons regenerating throu...
After a central nervous system (CNS) injury, there is only an "abortive regeneration" of axons, whil...
Axonal regeneration of septal cholinergic neurons was examined after lesion of the septohippocampal ...
In order to investigate whether a fibrin-fibronectin-containing matrix of a peripheral regeneration ...
Schwann cells (SCs) have been shown to be a key element in promoting axonal regeneration after being...
Injuries to the spinal cord induce distinct changes at the lesion site. Over recent years, it has be...
Schwann cells (SCs) have been shown to be a key element in promoting axonal regeneration after being...
The study was focused on responses of CNS neurons in adult rats to autologous tibial nerve grafts im...
The mature mammalian central nervous system (CNS) is unable to regenerate successfully after injury....
A neuronotrophic hypothesis for the adult central nervous system (CNS) has been increasingly support...
Spontaneous cellular reorganisation at the lesion site has been investigated following massive spina...
Spinal cord injury results in complete failure of the central neurons to regenerate and is associate...
Animal studies are now showing the exciting potential to achieve significant functional recovery fol...
In order to study the 'in vivo' regenerative capacity of the central nervous system, a semipermeable...
Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative ...
The present work elucidates the connectivity of adult retinal ganglion cell axons regenerating throu...
After a central nervous system (CNS) injury, there is only an "abortive regeneration" of axons, whil...
Axonal regeneration of septal cholinergic neurons was examined after lesion of the septohippocampal ...
In order to investigate whether a fibrin-fibronectin-containing matrix of a peripheral regeneration ...
Schwann cells (SCs) have been shown to be a key element in promoting axonal regeneration after being...
Injuries to the spinal cord induce distinct changes at the lesion site. Over recent years, it has be...
Schwann cells (SCs) have been shown to be a key element in promoting axonal regeneration after being...
The study was focused on responses of CNS neurons in adult rats to autologous tibial nerve grafts im...
The mature mammalian central nervous system (CNS) is unable to regenerate successfully after injury....
A neuronotrophic hypothesis for the adult central nervous system (CNS) has been increasingly support...
Spontaneous cellular reorganisation at the lesion site has been investigated following massive spina...
Spinal cord injury results in complete failure of the central neurons to regenerate and is associate...
Animal studies are now showing the exciting potential to achieve significant functional recovery fol...
In order to study the 'in vivo' regenerative capacity of the central nervous system, a semipermeable...
Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative ...
The present work elucidates the connectivity of adult retinal ganglion cell axons regenerating throu...
After a central nervous system (CNS) injury, there is only an "abortive regeneration" of axons, whil...