Polymorphisms in the region of the interleukin-28B (IL28B) gene have recently been associated with spontaneous and treatment induced clearance of hepatitis C virus infection. The specific mechanisms of how IL28B polymorphisms affect HCV suppression remain unknown. It is a matter of ongoing debate how to incorporate the IL28B data into the current treatment algorithms with pegylated interferon-alpha and ribavirin. The eventual role of the IL28B genotype in new therapeutic regimes with direct antiviral agents needs to be explored in the ongoing and future clinical studies with these agents
Host genetic factors may predict the outcome and treatment response in hepatitis C virus (HCV) infec...
Summary. Genetic polymorphisms near IL28B are associated with spontaneous and treatment-induced cle...
In 2009, an association between the interleukin-28B (IL28B) polymorphism and treatment outcome for g...
Polymorphisms in the region of the interleukin-28B (IL28B) gene have recently been associated with s...
Polymorphisms in the region of the interleukin-28B (IL28B) gene have recently been associated with s...
Recently, single-nucleotide polymorphisms near the IL28B gene have been identified as important in p...
Recent genome-wide association studies (GWAS) have identified genetic variations near the IL28B gene...
In the past 2 years the ability to successfully eradicate chronic HCV infection has been substantial...
Background: Interleukin (IL) 28B single nucleotide polymorphisms may play a role in the clearance of...
Three landmark genome-wide association studies (GWAS) published in 2009 identified the interleukin (...
Polymorphisms in the IL28B (interleukin-28B) gene region are important in predicting outcome followi...
Background: It has been shown that single nucleotide polymorphisms (SNPs) near the interleukin 28B (...
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the i...
In 2009, genome-wide association studies identified key roles for IL28B and ITPA polymorphisms in pr...
Background: The present study aimed to determine the frequency of the IL28B polymorphism rs8099917 i...
Host genetic factors may predict the outcome and treatment response in hepatitis C virus (HCV) infec...
Summary. Genetic polymorphisms near IL28B are associated with spontaneous and treatment-induced cle...
In 2009, an association between the interleukin-28B (IL28B) polymorphism and treatment outcome for g...
Polymorphisms in the region of the interleukin-28B (IL28B) gene have recently been associated with s...
Polymorphisms in the region of the interleukin-28B (IL28B) gene have recently been associated with s...
Recently, single-nucleotide polymorphisms near the IL28B gene have been identified as important in p...
Recent genome-wide association studies (GWAS) have identified genetic variations near the IL28B gene...
In the past 2 years the ability to successfully eradicate chronic HCV infection has been substantial...
Background: Interleukin (IL) 28B single nucleotide polymorphisms may play a role in the clearance of...
Three landmark genome-wide association studies (GWAS) published in 2009 identified the interleukin (...
Polymorphisms in the IL28B (interleukin-28B) gene region are important in predicting outcome followi...
Background: It has been shown that single nucleotide polymorphisms (SNPs) near the interleukin 28B (...
In a recent genome-wide association study, single nucleotide polymorphisms (SNPs) located near the i...
In 2009, genome-wide association studies identified key roles for IL28B and ITPA polymorphisms in pr...
Background: The present study aimed to determine the frequency of the IL28B polymorphism rs8099917 i...
Host genetic factors may predict the outcome and treatment response in hepatitis C virus (HCV) infec...
Summary. Genetic polymorphisms near IL28B are associated with spontaneous and treatment-induced cle...
In 2009, an association between the interleukin-28B (IL28B) polymorphism and treatment outcome for g...