Ecotoxicological and regulatory aspects of environmental sustainability of nanopesticides

From Elsevier via Jisc Publications RouterHistory: accepted 2020-09-28, epub 2020-10-12, issue date 2021-02-15Article version: AMPublication status: PublishedFunder: São Paulo Research Foundation; Grant(s): #2017/21004-5, #2019/20124-2Funder: CNPq; Grant(s): #427498/2018-0Funder: CESAM; Grant(s): UIDB/50017/2020, UIDP/50017/2020Funder: FEDERFunder: NANORIGO: Establishing a NANOtechnology RIsk Governance Framework; Grant(s): 814530Recent years have seen the development of various colloidal formulations of pesticides and other agrochemicals aimed at use in sustainable agriculture. These formulations include inorganic, organic or hybrid particulates, or nanocarriers composed of biodegradable polymers, that can provide a better control of the release of active ingredients. The very small particle sizes and high surface areas of nanopesticides may however also lead to some unintended (eco)toxicological effects due to the way in which they interact with the target and non-target species and the environment. The current level of knowledge on ecotoxicological effects of nanopesticides is scarce, especially in regard to the fate and behaviour of such formulations in the environment. Nanopesticides will however have to cross a stringent regulatory scrutiny before marketing in most countries for health and environmental risks under a range of regulatory frameworks that require pre-market notification, risk assessment and approval, followed by labelling, post-market monitoring and surveillance. This review provides an overview of the key regulatory and ecotoxicological aspects relating to nanopesticides that will need to be considered for environmentally-sustainable use in agriculture