Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.

Nyiraneza, Christine
Sempoux, Christine
Detry, Roger
Kartheuser, Alex
Dahan, Karin

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Publication date

January 2012

DOI

10.1186/1868-7083-4-9

Publisher

Springer Science and Business Media LLC

ISSN

1868-7083

Citation count (estimate)

Abstract

p14ARF epigenetic silencing may represent an important deregulating mechanism of the p53-MDM2-p14ARF pathway in CRCs exhibiting a restricted p53 overexpression pattern

Extracted data

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Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.

Abstract

Extracted data

Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.

Abstract

Extracted data

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