Nowadays several Computer-Aided Software Engineering environments exploit Model-Driven Engineering (MDE) techniques in order to generate a single user interface for a given computing platform or multi-platform user interfaces for several computing platforms simultaneously. Therefore, there is a need to assess the usability of those generated user interfaces, either taken in isolation or compared to each other. This paper describes an MDE approach that generates multi-platform graphical user interfaces (e.g., desktop, web) that will be subject to an exploratory controlled experiment. The usability of user interfaces generated for the two mentioned platforms and used on multiple display devices (i.e., standard size, large, and small screens) ...