Funding Information: Funding and additional information—This work was supported by EMPIR programme in Research Project 15HLT02 ReMiND cofinanced by the Participating States and the European Union's Horizon 2020 research and innovation programme (to N. L.). Work was also supported by WisTa Laboratories Ltd. (to V. M., D. L., M. M., C. R. H., G. R., C. M. W., F. T., and K. S.). Conflict of interest—This work was sponsored by WisTa Laboratories Ltd., an affiliate of TauRx Therapeutics Ltd. C. R. H. and C. M. W. are employees and officers of TauRx Therapeutics Ltd.Peer reviewedPublisher PD
Tauopathies, characterized by hyperphosphorylation and aggregation of tau protein, include frontotem...
One of the characteristics of Alzheimer’s disease and associated tauopathies is the accumulation and...
The aim of this PhD-thesis was to characterize single and double transgenic mouse models for Alzheim...
Funding Information: Funding and additional information—This work was supported by EMPIR programme i...
AbstractMany proteins that are implicated in human disease are posttranslationally modified. This in...
Funding: This research received no external funding. Acknowledgments: The authors acknowledge Boris ...
Thesis by publication.Bibliography: pages 120-152.1. Introduction -- 2. Disinhibition-like behavior ...
The hyperphosphorylated microtubule-associated protein tau is present in several neurodegenerative d...
AbstractHyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are...
Human tauopathies, such as Alzheimer’s disease (AD), have been widely studied in transgenic mice ove...
Tau is a neuronal microtubule associated protein whose main biological functions are to promote micr...
Intracellular tau aggregates are the neuropathological hallmark of several neurodegenerative disease...
Cytoplasmic inclusions and fibrils of the microtubule-associated protein tau (tau protein) are a key...
Acknowledgments: Depolymerised bovine tubulin was kindly donated by J. Kilmartin (MRC Laboratory of ...
Hyperphosphorylation and accumulation of tau in neurons (and glial cells) is one the main pathologic...
Tauopathies, characterized by hyperphosphorylation and aggregation of tau protein, include frontotem...
One of the characteristics of Alzheimer’s disease and associated tauopathies is the accumulation and...
The aim of this PhD-thesis was to characterize single and double transgenic mouse models for Alzheim...
Funding Information: Funding and additional information—This work was supported by EMPIR programme i...
AbstractMany proteins that are implicated in human disease are posttranslationally modified. This in...
Funding: This research received no external funding. Acknowledgments: The authors acknowledge Boris ...
Thesis by publication.Bibliography: pages 120-152.1. Introduction -- 2. Disinhibition-like behavior ...
The hyperphosphorylated microtubule-associated protein tau is present in several neurodegenerative d...
AbstractHyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are...
Human tauopathies, such as Alzheimer’s disease (AD), have been widely studied in transgenic mice ove...
Tau is a neuronal microtubule associated protein whose main biological functions are to promote micr...
Intracellular tau aggregates are the neuropathological hallmark of several neurodegenerative disease...
Cytoplasmic inclusions and fibrils of the microtubule-associated protein tau (tau protein) are a key...
Acknowledgments: Depolymerised bovine tubulin was kindly donated by J. Kilmartin (MRC Laboratory of ...
Hyperphosphorylation and accumulation of tau in neurons (and glial cells) is one the main pathologic...
Tauopathies, characterized by hyperphosphorylation and aggregation of tau protein, include frontotem...
One of the characteristics of Alzheimer’s disease and associated tauopathies is the accumulation and...
The aim of this PhD-thesis was to characterize single and double transgenic mouse models for Alzheim...