Parkinson’s Disease and the Immune System

The characteristic neuropathological markers of PD are the presence of Lewy bodies, containing modified alpha-synuclein amongst other proteins, in the surviving neurons, and the degeneration of neuromelanin-containing, dopaminergic neurons in the substance nigra pas compact region of the brain. In addition, the progressive nature of PD is characterized by chronic innate inflammation with microglial activation… open access: http://www.intechopen.com/books/mechanisms-in-parkinson-s-disease-models-and-treatments/innate-immune-system-and-parkinson-s-diseas