Listen to the frog! An auditory P300 brain-computer interface with directional cues and natural sounds

Severely disabled patients such as in late stage of amyotrophic lateral sclerosis (ALS) might lose eye gaze and thus, the ability to control an eye tracking system for communication. These patients are in the utmost need of brain- computer interfaces (BCIs). The paradigm presented here combined approaches of different auditory BCIs (Furdea et al., 2009, Klobassa et al., 2009, Schreuder et al., 2010, Käthner et al., 2013) by using natural sounds with directional cues as auditory stimuli for a P300 BCI. Natural sounds were selected as they showed best differentiation in a pretest