Vibrationally resolved fluorescence spectra of the beta-hairpin trpzip2 peptide at two temperatures as well as during a T-jump unfolding process are simulated on the basis of a combination of Markov state models and quantum chemistry schemes. The broad asymmetric spectral line shape feature is reproduced by considering the exciton-phonon couplings. The temperature dependent red shift observed in the experiment has been attributed to the state population changes of specific chromophores. Through further theoretical study, it is found that both the environment's electric field and the chromophores' geometry distortions are responsible for tryptophan fluorescence shift
From the temperature dependence of fluorescence quenching kinetics, a novel temperature-sensitive st...
Optical spectroscopic tools are used to monitor protein folding/unfolding dynamics after a fast trig...
The interactions of tryptophan-59 (TRP-59) and its protein environment in ribonuclease-T1 (RNAse-T1)...
Abstract: We proposed a computational protocol of simulating the T-jump peptide unfolding experiment...
International audienceRecent time-resolved lifetime measurements studied the quenching of the fluore...
Simulating the T-Jump-Triggered Unfolding Dynamics of trpzip2 Peptide and Its Time-Resolved IR and T...
AbstractTryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins a...
International audienceThe structures, dynamics and energetics of the protonated, derivatized peptide...
Thesis (Ph.D.)--University of Washington, 2012Tryptophan fluorescence is often used as a probe of pr...
ABSTRACT Tryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins ...
We analyzed, based on the theoretical spectroscopic modeling, how the differences in the folding lan...
In a case study on five homologous alpha-amylases we analyzed the properties of unfolded states as o...
Polyglutamine (polyQ) model peptides are ideally suited to analyze the involvement of glutamines in ...
Item does not contain fulltextIsotope-edited two-dimensional infrared spectroscopy has been used to ...
The structures, dynamics and energetics of the protonated, derivatized peptide DyeX-(Pro)<sub>4</sub...
From the temperature dependence of fluorescence quenching kinetics, a novel temperature-sensitive st...
Optical spectroscopic tools are used to monitor protein folding/unfolding dynamics after a fast trig...
The interactions of tryptophan-59 (TRP-59) and its protein environment in ribonuclease-T1 (RNAse-T1)...
Abstract: We proposed a computational protocol of simulating the T-jump peptide unfolding experiment...
International audienceRecent time-resolved lifetime measurements studied the quenching of the fluore...
Simulating the T-Jump-Triggered Unfolding Dynamics of trpzip2 Peptide and Its Time-Resolved IR and T...
AbstractTryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins a...
International audienceThe structures, dynamics and energetics of the protonated, derivatized peptide...
Thesis (Ph.D.)--University of Washington, 2012Tryptophan fluorescence is often used as a probe of pr...
ABSTRACT Tryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins ...
We analyzed, based on the theoretical spectroscopic modeling, how the differences in the folding lan...
In a case study on five homologous alpha-amylases we analyzed the properties of unfolded states as o...
Polyglutamine (polyQ) model peptides are ideally suited to analyze the involvement of glutamines in ...
Item does not contain fulltextIsotope-edited two-dimensional infrared spectroscopy has been used to ...
The structures, dynamics and energetics of the protonated, derivatized peptide DyeX-(Pro)<sub>4</sub...
From the temperature dependence of fluorescence quenching kinetics, a novel temperature-sensitive st...
Optical spectroscopic tools are used to monitor protein folding/unfolding dynamics after a fast trig...
The interactions of tryptophan-59 (TRP-59) and its protein environment in ribonuclease-T1 (RNAse-T1)...