Add to ORKGNeurotrophins are a family of trophic factors that has been established as pivotal players in the regulation of neuronal survival and differentiation throughout development and adulthood. The prototypic neurotrophin, nerve-growth factor (NGF), was isolated and purified more than 50 years ago as a target-derived trophic factor for developing neurons. Since then, not only were more members added to the family, but as our understanding of the neurotrophins advances, it became clear that the neurotrophins are involved in almost all aspects of neuronal development. Here we will summarize the critical roles of neurotrophins in the regulation of neuronal survival and apoptosis
Neuronal growth factors regulate the survival of neurons by their survival and death-promoting activ...
The 20th century has witnessed a slow but progressive convergence and tightening between neurologica...
The nerve growth factor family of neurotrophins play multiple roles in both the developing and matur...
Neurotrophins are a family of trophic factors that has been established as pivotal players in the re...
Nerve growth factor was the first identified protein with anti-apoptotic activity on neurons. This p...
The neurotrophins – NGF, BDNF, NT-3 – are secreted proteins that play a major role in neuron surviva...
It is beyond doubt that the neurotrophin family of proteins plays key roles in determining the fate ...
The neurotrophins are a small group of dimeric proteins that profoundly affect the development of th...
The Nerve Growth Factor (NGF) is the prototypic member of the neurotrophin (NT) family, which plays ...
AbstractNGF’s role in neuronal survival has tended to mask other potential functions. But now the ge...
The survival of the mammalian peripheral nervous system neurons has long been known to depend on neu...
Because the actions of neurotrophic factors appear distinct from those of traditional growth factors...
Neurotrophins (NTs) are molecules regulating differentiation, maintenance, and functional plasticity...
NGF's role in neuronal survival has tended to mask other potential functions. But now the generation...
AbstractIn the fifty years since its discovery, a substantial body of work has established that nerv...
Neuronal growth factors regulate the survival of neurons by their survival and death-promoting activ...
The 20th century has witnessed a slow but progressive convergence and tightening between neurologica...
The nerve growth factor family of neurotrophins play multiple roles in both the developing and matur...
Neurotrophins are a family of trophic factors that has been established as pivotal players in the re...
Nerve growth factor was the first identified protein with anti-apoptotic activity on neurons. This p...
The neurotrophins – NGF, BDNF, NT-3 – are secreted proteins that play a major role in neuron surviva...
It is beyond doubt that the neurotrophin family of proteins plays key roles in determining the fate ...
The neurotrophins are a small group of dimeric proteins that profoundly affect the development of th...
The Nerve Growth Factor (NGF) is the prototypic member of the neurotrophin (NT) family, which plays ...
AbstractNGF’s role in neuronal survival has tended to mask other potential functions. But now the ge...
The survival of the mammalian peripheral nervous system neurons has long been known to depend on neu...
Because the actions of neurotrophic factors appear distinct from those of traditional growth factors...
Neurotrophins (NTs) are molecules regulating differentiation, maintenance, and functional plasticity...
NGF's role in neuronal survival has tended to mask other potential functions. But now the generation...
AbstractIn the fifty years since its discovery, a substantial body of work has established that nerv...
Neuronal growth factors regulate the survival of neurons by their survival and death-promoting activ...
The 20th century has witnessed a slow but progressive convergence and tightening between neurologica...
The nerve growth factor family of neurotrophins play multiple roles in both the developing and matur...