Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Saccharomyces cerevisiae, two mechanisms contribute to spindle positioning. In the Kar9 pathway, astral microtubules emanating from the daughter-bound spindle pole body interact via the linker protein Kar9 with the myosin Myo2, which moves the microtubule along the actin cables towards the neck. In the dynein pathway, astral microtubules off-load dynein onto the cortical anchor protein Num1, which is followed by dynein pulling on the spindle. Yet, the mechanism by which microtubules target cortical anchor sites is unknown. Here we quantify the pivoting motion of astral microtubules around the spindle pole bodies, which occurs during spindle transloc...
In Saccharomyces cerevisiae, spindle orientation is controlled by a temporal and spatial program of ...
In the budding yeast Saccharomyces cerevisiae, the mitotic spindle must align along the mother-bud a...
When a spindle is positioned asymmetrically in a dividing cell, the resulting daughter cells are une...
<div><p>Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast...
Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Sacchar...
Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Sacchar...
In the budding yeast Saccharomyces cerevisiae, movement of the mitotic spindle to a predetermined cl...
AbstractBackground: Two genetic ‘pathways' contribute to the fidelity of nuclear segregation during ...
AbstractBackground: Two genetic ‘pathways’ contribute to the fidelity of nuclear segregation during ...
SummaryBackgroundBudding yeast is a unique model to dissect spindle orientation in a cell dividing a...
Localization of dynein–green fluorescent protein (GFP) to cytoplasmic microtubules allowed us to obt...
SummaryThe orientation of the mitotic spindle plays a key role in determining whether a polarized ce...
AbstractSpindle alignment is the process in which the two spindle poles are directed toward preselec...
AbstractRecent studies have significantly advanced our understanding of how a dividing cell asymmetr...
Spindle orientation is critical for accurate chromosomal segregation in eukaryotic cells. In the yea...
In Saccharomyces cerevisiae, spindle orientation is controlled by a temporal and spatial program of ...
In the budding yeast Saccharomyces cerevisiae, the mitotic spindle must align along the mother-bud a...
When a spindle is positioned asymmetrically in a dividing cell, the resulting daughter cells are une...
<div><p>Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast...
Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Sacchar...
Positioning of the mitotic spindle is crucial for proper cell division. In the budding yeast Sacchar...
In the budding yeast Saccharomyces cerevisiae, movement of the mitotic spindle to a predetermined cl...
AbstractBackground: Two genetic ‘pathways' contribute to the fidelity of nuclear segregation during ...
AbstractBackground: Two genetic ‘pathways’ contribute to the fidelity of nuclear segregation during ...
SummaryBackgroundBudding yeast is a unique model to dissect spindle orientation in a cell dividing a...
Localization of dynein–green fluorescent protein (GFP) to cytoplasmic microtubules allowed us to obt...
SummaryThe orientation of the mitotic spindle plays a key role in determining whether a polarized ce...
AbstractSpindle alignment is the process in which the two spindle poles are directed toward preselec...
AbstractRecent studies have significantly advanced our understanding of how a dividing cell asymmetr...
Spindle orientation is critical for accurate chromosomal segregation in eukaryotic cells. In the yea...
In Saccharomyces cerevisiae, spindle orientation is controlled by a temporal and spatial program of ...
In the budding yeast Saccharomyces cerevisiae, the mitotic spindle must align along the mother-bud a...
When a spindle is positioned asymmetrically in a dividing cell, the resulting daughter cells are une...