Add to ORKGThe in vivo antitumor activity of NCS-immune IgG (NCS conjugated with rabbit IgG antibody against the human leukemia cell line NALL-1) was evaluated in immunosuppressed newborn Syrian hamsters implanted with a transplantable human leukemia cell line (BALL-1). After i.p. injection of the conjugate, hamsters preinoculated i.p. with BALL-1 cells survived longer than hamsters treated with control solutions (p<0.01). The control solutions included NCS, immune IgG, a mixture of NCS and immune IgG, NCS-normal IgG conjugate and physiological saline. Growth retardation was not observed in NCS-immune IgG treated hamsters. The growth of s.c. implanted BALL-1 tumors was inhibited by i.p. administrations of NCS-immune IgG, however, the degree of inhibit...
Neocarzinostain (NCS) was first used by Hiraki and his colleagues for induction chemotherapy in acut...
Progress in three areas of research is summarized. These are as follows: Labeling Monoclonal antibod...
In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents to be used a...
The in vivo antitumor activity of NCS-immune IgG (NCS conjugated with rabbit IgG antibody against th...
In vivo antitumor activity of anti-Ia monoclonal IgM antibody (H-2)-Neocarzinostatin (NCS) conjugate...
A murine IgM monoclonal antibody specific for human Ia antigen was purified by Sephacryl S-300 chrom...
In the previous paper, we reported that Neocarzinostatin (NCS) could bind covalently to rabbit anti-...
Rabbit xenoantiserum was produced against a human null cell type leukemia cell line (NALL-1), and im...
Anti-NALL-1 rabbit IgG was incubated with NCS, an unique membrane-reactive anticancer antibiotic, in...
Human transferrin （Tf） was conjugated with the anticancer polypeptide, neocar- zinostatin （NCS）, by ...
Since tumor-antitumor agent-host correlation must be considered in the treatment of neoplasms, the q...
Antibody drug conjugates (ADCs) are monoclonal antibodies designed to deliver a cytotoxic drug selec...
The recent development of hybridoma technology, providing monoclonal antibodies (MoAb) of predefined...
In part 2 peripheral lymphocyte count, the total number of spleen cells, the weight and histology of...
Antibody drug conjugates (ADCs) are monoclonal antibodies designed to deliver a cytotoxic drug selec...
Neocarzinostain (NCS) was first used by Hiraki and his colleagues for induction chemotherapy in acut...
Progress in three areas of research is summarized. These are as follows: Labeling Monoclonal antibod...
In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents to be used a...
The in vivo antitumor activity of NCS-immune IgG (NCS conjugated with rabbit IgG antibody against th...
In vivo antitumor activity of anti-Ia monoclonal IgM antibody (H-2)-Neocarzinostatin (NCS) conjugate...
A murine IgM monoclonal antibody specific for human Ia antigen was purified by Sephacryl S-300 chrom...
In the previous paper, we reported that Neocarzinostatin (NCS) could bind covalently to rabbit anti-...
Rabbit xenoantiserum was produced against a human null cell type leukemia cell line (NALL-1), and im...
Anti-NALL-1 rabbit IgG was incubated with NCS, an unique membrane-reactive anticancer antibiotic, in...
Human transferrin （Tf） was conjugated with the anticancer polypeptide, neocar- zinostatin （NCS）, by ...
Since tumor-antitumor agent-host correlation must be considered in the treatment of neoplasms, the q...
Antibody drug conjugates (ADCs) are monoclonal antibodies designed to deliver a cytotoxic drug selec...
The recent development of hybridoma technology, providing monoclonal antibodies (MoAb) of predefined...
In part 2 peripheral lymphocyte count, the total number of spleen cells, the weight and histology of...
Antibody drug conjugates (ADCs) are monoclonal antibodies designed to deliver a cytotoxic drug selec...
Neocarzinostain (NCS) was first used by Hiraki and his colleagues for induction chemotherapy in acut...
Progress in three areas of research is summarized. These are as follows: Labeling Monoclonal antibod...
In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents to be used a...