This paper discusses two senses in which a hypothesis may be said to unify evidence. One is the ability of the hypothesis to increase the mutual information of a set of evidence statements; the other is the ability of the hypothesis to explain commonalities in observed phenomena by positing a common origin for them. On Bayesian updating, it is only mutual information unification that contributes to the incremental support of a hypothesis by the evidence unified. This poses a challenge for the view that explanation is a confirmatory virtue that contributes to such incremental support; its advocates must ground it in some relevant difference between humans and a Bayesian agent