5-Chloro-N-{4-oxo-2-[4-(trifluoromethyl)-phenyl]-1,3-thiazolidin-3-yl}-3-phenyl-1H- indole-2-carboxamide

  • Gurbuzel, Fusun Kazan
  • Celik, Ismail
  • Buyukgungor, Orhan
  • AKKURT, MEHMET
  • Ozkirimli, Sumru
Publication date
October 2012

Abstract

In the title compound, C25H17ClF3N3O2S, the five-membered 1,3-thiazolidine ring adopts a twist conformation. The three F atoms of the CF3 group are disordered over two sets of sites with refined occupancies of 0.542 (18) and 0.458 (18). In the nine-membered 1H-indoline ring system, the 1H-pyrrole ring forms a dihedral angle of 4.7 (2)degrees with the benzene ring, while it is twisted at an angle of 46.5 (2)degrees with respect to the attached phenyl ring. The dihedral angle between the phenyl and trifluoromethyl-substituted benzene rings is 56.0 (2)degrees. In the crystal, N-H center dot center dot center dot O hydrogen bonds connect the molecules into a three-dimensional network. In addition, weak C-H center dot center dot center dot O hyd...

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