A 15-year-old patient with cystic fibrosis with a disseminated Mycobacterium abscessus infection was treated with a three-phage cocktail following bilateral lung transplantation. Effective lytic phage derivatives that efficiently kill the infectious M. abscessus strain were developed by genome engineering and forward genetics. Intravenous phage treatment was well tolerated and associated with objective clinical improvement, including sternal wound closure, improved liver function, and substantial resolution of infected skin nodules
Antibiotics have saved numerous lives and still continue to do so. Their discovery brought about a r...
Lung disease, caused primarily by the bacterium Pseudomonas aeruginosa, is the leading cause of deat...
Mycobacterium abscessus infections are relatively common in patients with cystic fibrosis and are cl...
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosi...
Background: Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus, are incre...
Mycobacterium abscessus infections are common to patients with cystic fibrosis (CF) or non-CF bronch...
There is a global increasing number of Mycobacterium abscessus infections, especially pulmonary infe...
International audienceABSTRACT Infection by multidrug-resistant Mycobacterium abscessus is increasin...
Mycobacterium abscessus is a rapidly growing mycobacterium and an opportunistic pathogen mainly foun...
Bacteriophages are a promising therapeutic strategy among cystic fibrosis and lung-transplanted pati...
Mycobacterium abscessus is the etiological agent of severe pulmonary infections in vulnerable patien...
Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among cystic fibrosis...
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality ...
Background and Rationale. We have developed apoptotic body like liposomes (ABL) loaded withselected ...
Although early aggressive and prolonged treatment with specific antibiotics can extend survival in p...
Antibiotics have saved numerous lives and still continue to do so. Their discovery brought about a r...
Lung disease, caused primarily by the bacterium Pseudomonas aeruginosa, is the leading cause of deat...
Mycobacterium abscessus infections are relatively common in patients with cystic fibrosis and are cl...
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosi...
Background: Nontuberculous Mycobacterium infections, particularly Mycobacterium abscessus, are incre...
Mycobacterium abscessus infections are common to patients with cystic fibrosis (CF) or non-CF bronch...
There is a global increasing number of Mycobacterium abscessus infections, especially pulmonary infe...
International audienceABSTRACT Infection by multidrug-resistant Mycobacterium abscessus is increasin...
Mycobacterium abscessus is a rapidly growing mycobacterium and an opportunistic pathogen mainly foun...
Bacteriophages are a promising therapeutic strategy among cystic fibrosis and lung-transplanted pati...
Mycobacterium abscessus is the etiological agent of severe pulmonary infections in vulnerable patien...
Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among cystic fibrosis...
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality ...
Background and Rationale. We have developed apoptotic body like liposomes (ABL) loaded withselected ...
Although early aggressive and prolonged treatment with specific antibiotics can extend survival in p...
Antibiotics have saved numerous lives and still continue to do so. Their discovery brought about a r...
Lung disease, caused primarily by the bacterium Pseudomonas aeruginosa, is the leading cause of deat...
Mycobacterium abscessus infections are relatively common in patients with cystic fibrosis and are cl...