Add to ORKGThe salt (sodium chloride; NaCl) content of a western diet far exceeds the amount that we consumed through most of our evolutionary history. It is accepted that excess sodium intake causes hypertension and cardiovascular disease, but it has been recently shown that sodium also affects immunity, and high salt diets worsen animal models of autoimmune disease. Sodium has been shown to activate multiple immune cells, including Th17 cells, which provide protection from bacterial and fungal infection but which are also implicated in autoimmune disease. The mechanism by which sodium polarises Th17 cells, whether salt depletion has clinical consequences, and if altering sodium balance affects the development of inflammatory kidney diseases are unkn...
Recently, we have shown that high dietary salt intake aggravates T helper cell (Th) 17 responses and...
Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from f...
The incidence of allergic diseases has increased over the past 50 years, likely due to environmental...
Immune mediated diseases (IMDs) are complex chronic inflammatory diseases involving genetic and envi...
The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for ca...
The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for ca...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
The skin can serve as an interstitial Na(+) reservoir. Local tissue Na(+) accumulation increases wit...
The skin can serve as an interstitial Na(+) reservoir. Local tissue Na(+) accumulation increases wit...
Sodium intake is undoubtedly indispensable for normal body functions but can be detrimental when tak...
Sodium intake is undoubtedly indispensable for normal body functions but can be detrimental when tak...
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. A...
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. A...
Recently, we have shown that high dietary salt intake aggravates T helper cell (Th) 17 responses and...
Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from f...
The incidence of allergic diseases has increased over the past 50 years, likely due to environmental...
Immune mediated diseases (IMDs) are complex chronic inflammatory diseases involving genetic and envi...
The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for ca...
The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for ca...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
Background: There has been a marked increase in the incidence of autoimmune diseases like multiple s...
The skin can serve as an interstitial Na(+) reservoir. Local tissue Na(+) accumulation increases wit...
The skin can serve as an interstitial Na(+) reservoir. Local tissue Na(+) accumulation increases wit...
Sodium intake is undoubtedly indispensable for normal body functions but can be detrimental when tak...
Sodium intake is undoubtedly indispensable for normal body functions but can be detrimental when tak...
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. A...
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. A...
Recently, we have shown that high dietary salt intake aggravates T helper cell (Th) 17 responses and...
Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from f...
The incidence of allergic diseases has increased over the past 50 years, likely due to environmental...