We investigate the equilibrium charge distribution of dust grains in the interstellar medium (ISM). Our treatment accounts for collisional charging by electrons and ions, photoelectric charging due to a background interstellar radiation field, the collection of suprathermal cosmic ray electrons and photoelectric emission due to a cosmic ray induced ultraviolet radiation field within dense molecular clouds. We find that the charge equilibrium assumption is valid throughout the multiphase ISM conditions investigated here, and should remain valid for simulations with resolutions down to au scales. The charge distribution of dust grains is size, composition, and ISM environment dependent: local radiation field strength, G, temperature, T, and e...