Church interior, ceiling of the nave, showing painted wood; Mission Basilica San Diego de Alcalá, in San Diego was the first Franciscan mission in the Alta California region of New Spain. It was founded in 1769 by Spanish friar Junípero Serra in an area long inhabited by the Kumeyaay Indians. The mission and the surrounding area were named for the Catholic Saint Didacus, a Spaniard more commonly known as San Diego. The mission was the site of the first Christian burial in Alta California. The current church is the fourth to stand on this location. The Mission is a National Historic Landmark. The mission was constructed of adobe in a quadrangular configuration with an open courtyard, it (and the Presidio Real) was the first permanent structu...