Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography (MX) since the earliest days. Many approaches have been used to treat twinned data in order to extract structural information. However, in most cases it is usually simpler to rescreen for new crystallization conditions that yield an untwinned crystal form or, if possible, collect data from non-twinned parts of the crystal. Here, we report 11 structures of engineered variants of the E. coli enzyme N-acetyl-neuraminic lyase which, despite twinning and incommensurate modulation, have been successfully indexed, solved and deposited. These structures span a resolution range of 1.45–2.30 Å, which is unusually high for datasets presenting such latti...
Journal ArticleResearch Support, Non-U.S. Gov'tThe presence of pseudo-symmetry in a macromolecular c...
Different types of crystal twinning are reviewed with an emphasis on how to detect the phenomenon fr...
International audienceThe purification, crystallization and successful structure determination by mo...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
These 11 datasets were collected at the Diamond Light Source and belong to the same protein, NAL (N-...
These 11 datasets were collected at the Diamond Light Source and belong to the same protein, NAL (N-...
AbstractHexagonal crystals of the membrane protein bacteriorhodopsin of space group P63 grown in lip...
A detailed description of the procedures utilized in the nonroutine X-ray single-crystal structural ...
In the field of crystallography, some crystals are not made of a single component but are instead tw...
Journal ArticleResearch Support, Non-U.S. Gov'tThe presence of pseudo-symmetry in a macromolecular c...
Different types of crystal twinning are reviewed with an emphasis on how to detect the phenomenon fr...
International audienceThe purification, crystallization and successful structure determination by mo...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
Twinning is a crystal growth anomaly, which has posed a challenge in macromolecular crystallography ...
These 11 datasets were collected at the Diamond Light Source and belong to the same protein, NAL (N-...
These 11 datasets were collected at the Diamond Light Source and belong to the same protein, NAL (N-...
AbstractHexagonal crystals of the membrane protein bacteriorhodopsin of space group P63 grown in lip...
A detailed description of the procedures utilized in the nonroutine X-ray single-crystal structural ...
In the field of crystallography, some crystals are not made of a single component but are instead tw...
Journal ArticleResearch Support, Non-U.S. Gov'tThe presence of pseudo-symmetry in a macromolecular c...
Different types of crystal twinning are reviewed with an emphasis on how to detect the phenomenon fr...
International audienceThe purification, crystallization and successful structure determination by mo...