A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
- Early Growth Genetics Consortium
- Bradfield, Jonathan P.
- Vogelezang, Suzanne
- Pitkänen, Niina
- Leinonen, Jaakko T.
- Lindi, Virpi
- Atalay, Mustafa
- Kähönen, Mika
- Raitakari, Olli T.
- Eriksson, Johan
- Widen, Elisabeth
DOIAbstract
Although hundreds of genome-wide association studies-implicated loci have been reported for adult obesity-related traits, less is known about the genetics specific for early-onset obesity and with only a few studies conducted in non-European populations to date. Searching for additional genetic variants associated with childhood obesity, we performed a trans-ancestral meta-analysis of 30 studies consisting of up to 13005 cases (>= 95th percentile of body mass index (BMI) achieved 2-18 years old) and 15599 controls (consistentlyPeer reviewe
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