Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with D-glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial dysfunction in the placental endothelium and trophoblast. Additionally, GDM is associated with reduced placental oxidative phosphorylation due to diminished activity of the mitochondrial FF-ATP synthase (complex V). This phenomenon may result from a higher generation of reactive superoxide anion and nitric oxide. Placental mitochondrial biogenesis and mitophagy work in concert to maintain cell homeostasis and are vital mechanisms securing the efficient generation of ATP, whose demand is higher in pregnancy, ensuring foetal growth and development. Additional factors dis...
of mitochondrial biogenesis and function to maternal diabetes in rat embryo during the placentation ...
Prenatal growth restraint is associated with increased oxidative stress--as judged by mitochondrial ...
Gestational diabetes mellitus (GDM) imposes serious short- and long-term health problems for mother ...
Mitochondrial dysfunction is known to occur in diabetic phenotypes including type 1 and 2 diabetes m...
IntroductionGestational diabetes mellitus (GDM), a common pregnancy disorder, increases the risk of ...
Gestational diabetes mellitus (GDM), a common pregnancy disorder, increases the risk of fetal overgr...
Abstract Background The purpose of this study was to determine the mitochondrial content, and the ox...
Mitochondrial activity is critical for maintenance of correct glucose homeostasis and alteration in ...
Introduction: Maternal obesity (MO) and Gestational Diabetes Mellitus (GDM) represent risk factors ...
A lipotoxic placental environment is recognized in maternal obesity, with increased inflammation and...
Objectives: Mounting evidence highlights the importance of mitochondrial dynamics (MD), namely mitoc...
Mitochondria are central to cell function. The placenta forms the interface between maternal and fet...
Gestational diabetes mellitus (GDM) shows a deficiency in the metabolism of D-glucose and other nutr...
The placenta is essential for normal foetal metabolism and growth. However, maternal diabetes is an ...
Offspring of diabetic and obese mothers (ODOM) have greater risks of heart disease at birth and late...
of mitochondrial biogenesis and function to maternal diabetes in rat embryo during the placentation ...
Prenatal growth restraint is associated with increased oxidative stress--as judged by mitochondrial ...
Gestational diabetes mellitus (GDM) imposes serious short- and long-term health problems for mother ...
Mitochondrial dysfunction is known to occur in diabetic phenotypes including type 1 and 2 diabetes m...
IntroductionGestational diabetes mellitus (GDM), a common pregnancy disorder, increases the risk of ...
Gestational diabetes mellitus (GDM), a common pregnancy disorder, increases the risk of fetal overgr...
Abstract Background The purpose of this study was to determine the mitochondrial content, and the ox...
Mitochondrial activity is critical for maintenance of correct glucose homeostasis and alteration in ...
Introduction: Maternal obesity (MO) and Gestational Diabetes Mellitus (GDM) represent risk factors ...
A lipotoxic placental environment is recognized in maternal obesity, with increased inflammation and...
Objectives: Mounting evidence highlights the importance of mitochondrial dynamics (MD), namely mitoc...
Mitochondria are central to cell function. The placenta forms the interface between maternal and fet...
Gestational diabetes mellitus (GDM) shows a deficiency in the metabolism of D-glucose and other nutr...
The placenta is essential for normal foetal metabolism and growth. However, maternal diabetes is an ...
Offspring of diabetic and obese mothers (ODOM) have greater risks of heart disease at birth and late...
of mitochondrial biogenesis and function to maternal diabetes in rat embryo during the placentation ...
Prenatal growth restraint is associated with increased oxidative stress--as judged by mitochondrial ...
Gestational diabetes mellitus (GDM) imposes serious short- and long-term health problems for mother ...