Background: Pentraxins (PTX) play key roles in innate immunity and inflammatory responses. An increase in PTX3 levels may be a marker of early radiation injury in the lung. Thus, we aimed to determine the effect of radiation on PTX3 expression in a lung injury mouse model. Materials and Methods: Twenty-four 6-8-week-old mice were divided into 4 groups, one control (group 1) and three experimental groups (groups 2-4) irradiated with 6 MV photons and 5 Gy in a single fraction. Groups 2, 3, and 4 were sedated and euthanized 24, 72, and 168 h after radiation, respectively. The right lung middle lobe was then removed for histochemical examination and immunostaining for PTX3 expression, which was evaluated semiquantitatively using H-SCORE analysi...
The pentraxin superfamily is a group of evolutionarily conserved proteins that play important roles ...
Pneumonitis and fibrosis are major lung complications of irradiating thoracic malignancies. In the c...
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonar...
Mechanical ventilation is the major cause of iatrogenic lung damage in intensive care units. Althoug...
Innate immunity plays key roles in activation and orientation of adaptive immunity and consists of a...
Objective: Long pentraxin PTX3 is an inflammatory mediator and a component of the humoral arm of inn...
BACKGROUND/AIMS: It is well recognized that all aerobic cells have the protective mechanisms in orde...
Models of thoracic irradiation have been developed as clinicians and scientists have attempted to de...
Background: Radiotherapy is widely used in the treatment of lung cancer, with both curative and pall...
Purpose: Pulmonary inflammation is an adverse consequence of radiation therapy in breast cancer. The...
Klebsiella pneumoniae is a common pathogen in human sepsis. The emergence of multidrug-resistant K. ...
BACKGROUND: The radiation-induced lung injury is a common complication from radiotherapy in lung can...
This record contains raw data related to article “The Long Pentraxin PTX3 Controls Klebsiella Pneumo...
Pulmonary fibrosis is a progressive scarring disease of the lungs, characterized by inflammation, fi...
INTRODUCTION: Stereotactic ablative radiotherapy is a newly emerging radiotherapy treatment method t...
The pentraxin superfamily is a group of evolutionarily conserved proteins that play important roles ...
Pneumonitis and fibrosis are major lung complications of irradiating thoracic malignancies. In the c...
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonar...
Mechanical ventilation is the major cause of iatrogenic lung damage in intensive care units. Althoug...
Innate immunity plays key roles in activation and orientation of adaptive immunity and consists of a...
Objective: Long pentraxin PTX3 is an inflammatory mediator and a component of the humoral arm of inn...
BACKGROUND/AIMS: It is well recognized that all aerobic cells have the protective mechanisms in orde...
Models of thoracic irradiation have been developed as clinicians and scientists have attempted to de...
Background: Radiotherapy is widely used in the treatment of lung cancer, with both curative and pall...
Purpose: Pulmonary inflammation is an adverse consequence of radiation therapy in breast cancer. The...
Klebsiella pneumoniae is a common pathogen in human sepsis. The emergence of multidrug-resistant K. ...
BACKGROUND: The radiation-induced lung injury is a common complication from radiotherapy in lung can...
This record contains raw data related to article “The Long Pentraxin PTX3 Controls Klebsiella Pneumo...
Pulmonary fibrosis is a progressive scarring disease of the lungs, characterized by inflammation, fi...
INTRODUCTION: Stereotactic ablative radiotherapy is a newly emerging radiotherapy treatment method t...
The pentraxin superfamily is a group of evolutionarily conserved proteins that play important roles ...
Pneumonitis and fibrosis are major lung complications of irradiating thoracic malignancies. In the c...
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonar...