TEMPORAL BONE CARCINOMA: A NOVEL PROGNOSTIC SCORE BASED ON CLINICAL AND HISTOLOGICAL FEATURES
- Elisabetta Zanoletti
- Leonardo Franz
- Diego Cazzador
- Sebastiano Franchella
- Leonardo Calvanese
- Piero Nicolai
- Antonio Mazzoni
- Gino Marioni
DOIAbstract
Background This study aimed to develop a novel temporal bone carcinoma (TBSCC) prognosis scoring system and compare it with the revised Pittsburgh staging system. Methods Forty-four consecutive TBSCC patients were assessed to identify predictors of recurrence. Each predictor’s hazard ratio for recurrence was used to develop our novel scoring system. Results Based on variables with p<0.10 in Cox’s regression model, our score included: revised Pittsburgh stage; non-anterior spread of T4 carcinoma; dural involvement; and histological grade. A higher recurrence rate (p=0.000), and shorter disease-free survival (p=0.000) were associated with scores of ≥5. The AUC of our score was larger than that of the revised Pittsburgh stage for both...
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