Rast plijesni i nakupljanje aflatoksina u prisutnosti novosintetiziranth analogona dehidracetne kiseline

Dehydroacetic acid (DHA) and its newly synthetized analogues, 4-hydroxy-3(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (DHT) and 5-bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolil)-2H-pyrane-2-one (BrDHT), were tested for antifungal and antiaflatoxigenic acitivity in experiments with the aflatoxigenic mould Aspergillus parasiticus NRRL 2999. DHT and DHA concentrations of 3.0 µ.M and 6.0 µ.M respectively stimulated mould growth and aflatoxin B, and G, synthesis, but concentrations higher than 30.0 µ.M produced an inhibitory effect. In the presence of low BrDHT concentrations mould growth decreased by 70% and toxin concentrations by 85% and 90%, respectively.lstražen je utjecaj dehidracetne kiseline (DHA) i njezinih novosintetiziranih analogona, 4-hidroksi-6-(p-tolil)-3-(p-toluil)-2H-piran-2-ona (DHT) i 5-bromo-4-hidroksi-6-(p-tolil)-3-(p-toluil)-2H-piran-2-ona (BrDHT). na rast aflatoksinogene plijesni Aspergillus parasiticus NRRL 2999 i nakupljanje aflatoksina. Koncentracije DHA i DHT od 3.0 i 6.0 µ,M stimuliraju. a koncentracije više od 30.0 µ,M tih spojeva inhibiraju rast plijesni i proizvodnju aflatoksina. U pokusima s niskim koncentracijama spoja BrDHT. reduciran je rast plijesni do 70%. a koncentracije aflatoksina 81 i 01 bile su reducirane do vrijednosti od 85 odnosno do 90% u odnosu na kontrolne pokuse