Clinical presentations of cystic fi brosis in adulthood

Životni vijek bolesnika sa cističnom fi brozom stalno se produžuje zahvaljujući medicinskim spoznajama i njihovoj implementaciji u praksi, što utječe na porast broja odraslih bolesnika. Dužinom životnog vijeka mijenjaju se epidemiološki pokazatelji bolesti te se uočava sve više njenih komplikacija na drugim organskim sustavima. Stoga strategija za daljnje poboljšanje kakvoće života i životnog vijeka bolesnika sa cističnom fi brozom mora uključiti i preventivno djelovanje, kako bi se izbjegle, umanjile ili odgodile komplikacije u kasnijoj dobi.Medical care for individuals with cystic fi brosis has resulted in dramatic improvement in survival and subsequently a signifi cant change in the epidemiology of cystic fi brosis, bringing new challenges for patients and professionals. With an increasing number of patients reaching adult age, the impact of nutritional compromise and chronic infl ammation on diff erent organ systems has become increasingly manifest. The potential long term eff ect of medical interventions and therapies in early life, which aim to avoid, minimize or delay complications that occur later in life, should be considered as part of the strategies infl uencing the patient quality of life and long vitality